2020-21 Academic Catalog

This course explores the relationship between structure and reactivity in organic molecular systems, with an emphasis on reaction mechanisms. Topics include molecular orbital theory, stereoelectronic effects, linear free energy relationships, and kinetic isotope effects. We will use these theories to revisit and deepen our understanding of reactions from Chemistry 233 (Organic Chemistry & Lab) and 234 (Organic Chemistry II & Lab). We will then analyze additional classes of reactions, such as pericyclic, enantioselective, and organometallic transformations. Students will use the primary literature to further investigate these topics. Prerequisite: Chemistry 234; Either previous or concurrent registration in Chemistry 301, 343 or 344